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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f27c2ee21c85c05d4ab021577c8d2774e1822430f3be99a1f0ce1bb83a49231' 
  AND token = 'XFK5DBqEsdKBuNFN6NWD615N0o/KG+IogHveNyUvM3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}