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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c27e140536bb53a746535ae36cd73d32ad5e7fa361154895a05816ed1543229' 
  AND token = '0ykLotJft8f/ucImp6KEUSm94x+alqXCHE40mcP2Dho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}