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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df529ade7bb8f95e1b62a7f8c3edc5a3f548175334472d67b4f67d508ff7f293' 
  AND token = 'myQgfoFjJdgPHkcAMttoSkkC1PQjsoCW1dRBQ6UitLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}