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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3b833ce99ceeac1098a6f50f0fedba27669c7d2b45a4af8ea47e1665bc59f19' 
  AND token = 'IYzglU94mt6rb8Yvk9lQ3aJXnAB1DuGfPO7Xye0ewVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}