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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '516d8a41f8bd93fb7ed93a812c751b2758a01e8d0a0ba730f347b369eb9dc6d6' 
  AND token = 'eoWLoUt/UYnlxwLj0+Su8NjcYcz4FchFSpytsZ2wByM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}