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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea6289cd90d08883f5ad17bf6e2f1d7914e399fd0cd6c272ad8b5490127cad2' 
  AND token = 'K9gtq9T59IMU2dy7mLdDEaW9YLIZ4f/3uRNkQ+mKOzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}