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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec2ecb6d38f6697914eb2668871212c43a2995bac819e3187c5a8dbf35ca193' 
  AND token = 'f3TcUxiyhgjuK9njUm5n4f1GrpWfiW8Q1vm/m58AwHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}