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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e5cca6f7f485a163599d05b8d88dcb519cc18983a4ccee74fb02151cf4c626' 
  AND token = 'Q7Q3L6Bt48q7rAhIIf1GgkqdBEGQIRERDYdd39GMlKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}