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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf524a2b0c46a8d35fa35596655ba915dda725eb7fd0e745f68a40083c92f749' 
  AND token = 'C3b2brzC6LWTTGbKjTtsRrh50gUs0M+9CEJTF74f7Kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}