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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7581fa672ecc9220f6fb0bd34eb52b1498b2c0a49dbbb43ea83f8dad63accde8' 
  AND token = 'PYg79mo5wClcFaFIxUwJV9FGB8Ayc/lQ0BGMceRHaRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}