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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd528595409df5e5cf7da7611da3631e24011f9005e848691920c3065fe221455' 
  AND token = 'mjJosw1/xIvtvc73mTjCdli4TE9A4VolZdnohWBZZ4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}