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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1626e343608b678d58f10ebfe0132cf172283ed55bc9d0d8a1d88486a0da3ff0' 
  AND token = 'FNMiG6M7GuVf642XZi5Kk8bNpgt/pkZe1uHZdB5MSpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}