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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46eecd8cc22d9cfe5e34027816cca78697fd077315ecadb49cfe5af7ff0709ed' 
  AND token = 'K3v9OfVPjTeOBVrWqqrG7l1KiJfjBnI9zLeiacw5DHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}