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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0543eb0c6e01f27de09b8dc4b78c4ed0ca2774c23d27b7561776a4aa05467ce' 
  AND token = 'JIkjPfO8xAMKfimgaG6j7Vs75/Hbqe25bpGXpPuD/8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}