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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c1cbfc769b87a0110fe22470e85be37fe7a838330520990613f57074e75734b' 
  AND token = 'INerZpjYQBgvQ3h9pwoox+EYFQmGZst2YW3/TMaQO3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}