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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d4a8e6b5cad4fa4705fa0cb0ef884dd0d837309733526183491f1e76b01e8aa' 
  AND token = 'wZJHUFypW2+7SEEYSIR0HxgwACEg5SeAXALgpTFcJy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}