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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4c2171ba9fb02c99e5b1f56bdf6489395302f5df25334dbb677f8569531f8fa' 
  AND token = 'twNkQKkkRAEnRkI/+ygDLF8VUP6onTjcs0FHuAMuwfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}