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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22adba1d45cc2e8281181de213b5a8f097cca945f87094b1398d7553c5b36393' 
  AND token = 'hiTS0gdxfr7oYeFEJ/Sp7qkOPjYByroIFPEjuIWaolU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}