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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dadc76c07bd41beab43cabd17f999dd43bfcd842ce47a6e5b511883ac8213a7' 
  AND token = '7Y/xcOHr04CA165jH7KdvhgjFBhPmTGGIQfVQh0OB1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}