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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '924b071292e53682223d9670eac016eebe98e7e67d93016f122cd3e718537aa1' 
  AND token = 'Mb9jEORQfRF6kggOxWfe+uxN4/JC1L1MZ9bq+4VEGw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}