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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59fdb745704e331b1ef6a9475a64afd4500e862a261679c7b0afe146313cd88b' 
  AND token = '4+Y+L78964Mpb4jbmcF531xIOJQjVBh8YWtiIU9WKjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}