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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47374e5cac4d36fe4212b232a21959732198f1d588d87fae8e293e2941db8b5f' 
  AND token = '79UOO33S/Fy2c5bgxMmFunnhW/zELxSFBYLuXkGXIh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}