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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859005b50b40cfabcb9c8460f2982156784d4e26996e6e0fc2730e313dbee6d3' 
  AND token = 'QI23Xv0R0VaF/v8qtEQ34/i3ctGPjD0pijKhVBoXSIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}