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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a944bf024a0d2f7b5f4e395e53ed6af93a385de72f31162393929202f8a043' 
  AND token = 'QD7mPAz7naESPkcFXn6ejYFc/bjPuwkWqC3M7TT5+Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}