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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '648a921c8051251d65fe13b52bef00c015b11fcbff3e54b726e99b99745008c6' 
  AND token = '9wnJeLtujLrLYK/xdhYZNWpStjebLQQbeUC9J5VIBDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}