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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91c6fdaf65701432d0f46b676b9b8e9d13c16f61aab9440f8c8ee288bd9348f4' 
  AND token = 'c5XB7nB7CdLv+HbhaGkhNkznMq3fVOGWuL8VkCwOLT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}