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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7a6f7620c627bef06dde63bf926f5fbaf91328adbe48da71a1e156889890957' 
  AND token = '5abkN/WIM4JswpN9PLEpOlXdT72dfIXPt4Sgg6Yf0pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}