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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0263af4c06bbba046ab7d379e9b0a110a1175287b92774eb48245cb15fb17474' 
  AND token = 'MYL8l9l3ILprv/Z/2+K4f7aWPgu+csyiTsFw0ugpigQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}