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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c264bc4d0406c63cd327348cfb787b542c55f66b655780c35c351c969e31f0d0' 
  AND token = 'YPynn7c6Qo75ufTWAMj5HJVGA4XTBPGxpjuPi9h0Bzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}