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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d02183893d083f65646da3f6053e3fd3857a52e4f6bd6f7af96dd7197ff53d4' 
  AND token = 'gNjOXk9WLUOorr/5Qh5WSW+QDeZ8wAhZkIhZKm+ysDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}