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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '363314794a2486625f0401bf241520e8b1680b4dc4db0a7a41e2fbf36bbaaaea' 
  AND token = '6DcqG3oqNsZwN7skXo1eoCPpwdBw9aZ1p7qtlaPqHRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}