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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad1091f584f6d51396e44d2b7edc13f127c79e71297bbafa29c93d26ad47ebae' 
  AND token = '7sMM7nU9qnl7IyHVE/RDHMr8PKO5cSH+7qyqelhB+Hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}