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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a38d37a750524272e43686a6c73edd462a70640c8793845a7d76e2838007a9be' 
  AND token = 'Ss53IZgzKC5jDvZF6W6rN4rTvgAZHQGHzWQOF3NjV64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}