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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b94867f7ac022c038170235080007222422474ac8a4e293a50a0044e3da66dd' 
  AND token = 'dNJ5rL3qnUswSeQn+y4grezD4VW9/AkqhNrGtVNJZUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}