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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ae9e6d77afac0d3e538f87a61d6f1d09046150c7d446c92b3954d0a0ca019a1' 
  AND token = 'E2BLbQLl2X+DvIkIMdsa5kH7lgHgSEbIXAeoYNflnyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}