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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab0131b95e7e3e595a31d667c1749bddc6ffdd9f18f2eb04bed93a0ed6665710' 
  AND token = 'ATNE8eHP5PqdcCkqO+u3KTAIHbxLAPkmK7oDrjAAP88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}