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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54fb354af9886d958efc2b242a27eadf2587e9afcb4fdbc9a9b6db228920ff88' 
  AND token = 'VB3TGpfdg60P/iVVrFt54BOj8qmP0wpliiZjdW2uV1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}