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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70379c9fd18adb19a5c0529a6a1da1db9d07b96d4c517d9b56e6f3bb2f240a32' 
  AND token = 'S0F275A1FzStgmh6o7I2WvhcdwgPbl/SdTnbEvLHoX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}