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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8a45bd83ef40ca2a33f9929376bec12f0319bd4454d83e2c01b44e1b54d6a20' 
  AND token = 'ZEDetg1enxKQDdtzanMC1ma7+9TLqNndFxbeZPavn0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}