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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25cd6b5fe4a963c12a448365cd256711e2c6f882d5d40c3135f77c5204becb3' 
  AND token = 'TdGY3P46aQkNCOAp2yuC3TTC/p66TbFg/l8L+ghyvaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}