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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d325acd04f0cc4870ba67f2df283e72a383a1284c124f399f31b42603cae64' 
  AND token = 'SzbrE8KZvaEeGdeJk3L99wUd/IFq+haRgTox+H1p1Fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}