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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8101c4d94dfa6bc958f4d0f6319fcb96e44954a04df3c0437cd42768f5f6e739' 
  AND token = 'irYPHieihcuxbo2RFYLy1lb/Xs0dWTa1xxN0ZvguI28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}