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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ccf85e9d39f0cbc099e7a6172359f67e4b82b2bad50cf25b531f0777ac34aa4' 
  AND token = '4jgH+Qkf6A8lbunDbLFxS9FlLDKSfSr6fp2Avet6CE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}