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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c8f30dd31028c10e1d8a3795c7af4b86dd2524d71cce45f4dd46a366078a93' 
  AND token = 'DC35XhFS6YbV/WWOTCRtkdMon36WxpCOpWkz0VpLswE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}