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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9333ddcd53b636cd03139dac5c06fc797340797c0e3ce686b8365b24e58d820' 
  AND token = 'yP0Y0wMIEub2NOp9Z40ZrJVYTV7xAYEpGi3FMhQC7KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}