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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be7c21c31ab0a24bcb63efe57df022d877e770ecde7e55fb199c65500d496e44' 
  AND token = 'oT1sk7eEvD7MYl+mwu28BQv/LMV5soB1fSThTlsH0GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}