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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4a5cc8e73e1cd3de3245c842ed653d0802ac284436239eafe78155c9f0f74c1' 
  AND token = 'fD/jT+nvtQOLhlUIbdlbtLIdoJHuaR6KX/ppe0Fy9SI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}