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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ce3ca8153d586c50198285c1a15eebae0c1b22922a5d9db05c49c1d1ab007dc' 
  AND token = 'KHyWkop+hP/irwjxSAcJGToH4B1CYtUdijzT6DEmxbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}