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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '423847909e07ddbe342fbf04a1a9a58cb6d4e51f1762d43c785b5784295e4a39' 
  AND token = 'wehGOvRrA0jjR//IMbFlyj1wkJnINA2AsoQ1LNQmzfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}