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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6deb5dc6fe7edb1d227a253087175211cbdc86b2831d63f35edb78d18a19a2db' 
  AND token = 'MbIxuWb0i7m/HNA5XIVK+h6S5hNTMu0T6V+SsbJ7W/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}